I am finalising my PhD in biomedical sciences with special emphasis on hypoxia signalling and tumor-stroma interactions in the field of oncology. During this period I have obtained the skills required to manage my projects (i.e. time management, scientific writing, presenting, performing experiments, ...) which lead to the successful publication of several manuscripts (2 first authorships).
Currently, I am looking for a new challenge in the life sciences industry.
PhD student Leuven, Belgium
Since September 2010
As Master student at the lab of Molecular Oncology under the promotership of Massimiliano Mazzone, I was involved in the project on the role of the oxygen sensor Prolyl Hydroxylase domain protein 2 (PHD2) in chemotherapy side-toxicities and it’s delivery to the tumor. Continuation of this project during the start of my PhD resulted in a first authorship in Cancer Cell. In the meantime, I started up an ambitious project to unravel the protein interactome of PHD1, 2 and 3. One of the interactors of PHD1, 2 and 3 is the well-known tumor suppressor p53. This research intertwines hypoxia and p53 signalling and provides evidence for an increased sensitivity towards chemotherapy upon PHD1 blockage. This story is recently published at EMBO Molecular Medicine.
- Managing my PhD project
- Scientific writing (research grants and publications)
- Performing lab experiments
- Presentation of my project and relevant literature
- Management of mice colonies
- Guidance of master students Biomedical Sciences
- Communication with Belgian TV and radio upon publication in Cancer Cell
- Guided tours and project explanations to high school students (VIB Scientists at work) and “Stichting tegen kanker”
Analytical thinkingEfficiencyInterest in knowledgeProblem solvingCollaborationIndependence
oncologyPowerPoint Cell biology Animal models R&D Scientific writingAnimal ModelsCancerCell CultureWestern BlottingCommunication SkillsDatabase design and maintenanceDNA extractionEnglishImmunohistochemistry (IHC)ImmunofluorescenceImmunoprecipitationmolecular biologyMolecular Cloning
Skills and Expertise
Develop protocols Guide students Write papersAdjust methodsCoachCollaborate with principal investigatorCollaborate with project teamConduct literature searchesConduct research at universitiesDesign protocolWrite protocolsWrite papersUse western blotting techniqueSupervise techniciansSolve problemsInterpret dataManuscript reviewPresent data at congressPresent at steering committee
Master in Biomedical Sciences from KU Leuven in 2010
Bachelor in Biomedical Sciences from KU Leuven in 2008
Training and Certification
Felasa B laboratory animal science in 2008 Certification
Expert has 2 publications (Will be avalible with full profile)