Since July 2016
Since July 2012
I joined the Ovaa lab as a Marie Curie Fellow and have been involved in the development of a mechanism-based activity probe targeting the E1-E2-E3 ubiquitin enyzme cascade. Currently, I'm expanding the concept of this founder probe to other ubiquitin-like modifiers and am exploring the underlying biology.
November 2011 --- June 2012
During my diploma thesis, I investigated the modulatory effect of small molecules on proteasome activity using different techniques including flow cytometry, biochemical and cell based assays, as well as qPCR.
January 2011 --- January 2011
“Heterlogous expression of various type III antibiotics” - Cultivation of bacterial strains - Cloning and expression - Mass spectrometric analysis of metabolites (MS/MS)
May 2010 --- August 2010
"Purification and in vitro assays of different LABKC mutants for elucidation of the Labyrinthopeptin-A2 biosynthesis" (Supervision of Prof. R. Süssmuth).
January 2008 --- January 2009
- Fermentation, Purification and Generation of Abyssomycin C derivatives - Semisynthetic approaches for validation of possible biosynthetic routes of Abyssomycin C derivatives (Supervision: Prof. Roderich Süssmuth)
January 2008 --- January 2008
Supervison: Dr. Ulrike Schimpf
Diploma in Chemistry from Technische Universität Berlin in 2012