BrightOwl Loader Loading

Summary

i’m a PhD student in the group of prof. huib ovaa, which focuses on generating ubiquitin and ubiquitin-like reagents. my main focus is on developing and validating a unique transferrable activity-based probe targeting the e1-e2-e3 ubiquitin Enzyme cascade. with this groundbreaking probe available, i’m currently applying it to elucidate outstanding Biological questions as well as expanding the concept to ubiquitin-like modifiers.

Experiences

Current Experience

  • PhD student


    Since July 2016

  • PhD student


    Since July 2012
    i joined the ovaa Lab as a marie curie fellow and have been involved in the development of a mechanism-based activity probe targeting the e1-e2-e3 ubiquitin enyzme cascade. currently, i'm expanding the concept of this Founder probe to other ubiquitin-like modifiers and am exploring the underlying Biology. I joined the Ovaa lab as a Marie Curie Fellow and have been involved in the development of a mechanism-based activity probe targeting the E1-E2-E3 ubiquitin enyzme cascade. Currently, I'm expanding the concept of this founder probe to other ubiquitin-like modifiers and am exploring the underlying biology.

Past Experience

  • Intern

    November 2011 --- June 2012
    during my diploma thesis, i investigated the modulatory effect of Small molecules on proteasome activity using different techniques including Flow Cytometry, biochemical and Cell based Assays, as well as qPCR.

  • Intern

    January 2011 --- January 2011
    “heterlogous expression of various type iii antibiotics” - cultivation of bacterial strains - cloning and expression - mass spectrometric Analysis of metabolites (ms/ms)

  • Intern

    May 2010 --- August 2010
    "Purification and In Vitro Assays of different labkc mutants for elucidation of the labyrinthopeptin-a2 biosynthesis" (supervision of prof. r. süssmuth).

  • Intern

    January 2008 --- January 2009
    - Fermentation, Purification and generation of abyssomycin c derivatives - semisynthetic approaches for Validation of possible biosynthetic routes of abyssomycin c derivatives (supervision: prof. roderich süssmuth)

  • Summer Internship

    January 2008 --- January 2008
    supervison: dr. ulrike schimpf

Knowledge

LinkedIn Assessment :
molecular biologyCell biologyCell CultureWestern BlottingPCRBiochemistryLifesciencesFlow CytometryqPCRscienceImmunologyCancer ResearchLife SciencesChemistryReal-Time Polymerase Chain Reaction (qPCR)Polymerase Chain Reaction (PCR)ResearchPurificationProtein chemistry

Education

  • Diploma in Chemistry from Technische Universität Berlin in 2012

Area / Region

Netherlands

Others

Driving License
  • No

Similar Candidates

Other Candidates in Netherlands

Other similar Candidates in this location (country / city)

Other Candidates

Most Recent Searches

Most Famous Searches

You might also like