PhD Candidate Barcelona, SpainSeptember 2011 --- July 2015
i have been working in the search of Biomarkers of disease progression in familial amyloid polyneuropathies related to transthyretin. to this purpose, i have worked with human serum samples, being in charge of its reception, its organization in a database and its processing. i have been responsible of the development of a new methodology for the analysis of the samples through LC-MS analysis and high-resolution extracted ion chromatogram (hr-xic) based quantification, leading to a publication in journal of Proteomics. in addition, i am familiar with sample manipulation protocols for proteomic analysis as well as several Mass Spectrometry instruments, techniques and proteomic Software for processing and Data Analysis, as detailed in my cv.
Supervisor of master thesis students Barcelona, SpainSeptember 2011 --- August 2012
- MSc isadora bassetto kwiatkowski "e. coli recombinant production of transthyretin, bioreactor scale"
- MSc ellen yadira cotrina celis "transthyretin-related amyloidosis: new families of fibrillogenesis inhibitors"
Master Thesis Barcelona, SpainSeptember 2010 --- July 2011
i performed the In Vitro screening of a library of possible transthyretin fibrillogenesis inhibitors selected by a bioinformatic repurposing workflow, finding new potential candidates for ttr amyloidosis Treatment. in addition, i acquired expertise in recombinant Protein Expression, Purification and Characterization and in In Vitro HTS drug Assays.
Research internship Granollers, SpainJuly 2008 --- August 2008
Student Job Puigcerdà, SpainJune 2003 --- June 2008
shop assistant and babysitting at stationery shop in my home town during weekends and holidays.
AdaptabilityAnalytical thinkingAttention to detailCommunicativeInterest in knowledgeOrganizationProblem solvingResponsibilityResult OrientedSociabilityTrustSelf-disciplineCollaborationFlexibilityCuriosityIndependence
Proteomics R&DChromatographyMass SpectrometryProtein ExpressionProtein chemistryDevelop ProtocolsInterpret dataInteract with physiciansReport data BiochemistryBiotechnologyProtein PurificationHTSLife SciencesLC-MSMALDI-TOFMALDI-TOF/TOFMS data analysisPeptide mass spectrometryLC-QQQTargeted proteomicsIntact protein mass spectrometryBiotools 3.2 (Bruker Daltonics)Flex Analysis 3.3 (Bruker Daltonics)ProteinScape 3.1 (Bruker Daltonics)Data Analysis 4.1 (Bruker Daltonics)Skyline (MacCoss Lab)MultiQuant (AB Sciex)Analyst (AB Sciex)Mascot (Matrix Science)MaXis Impact Q-TOF (Bruker Daltonics)MALDI-TOF Autoflex Speed (Bruker Daltonics)Ion Trap HCT Ultra PTM Discovery System ETDII (Bruker Daltonics)4000 QTRAP Triple Quadrupole (AB Sciex)HPLCnano LCChromatographyWestern Blotting
Skills and Expertise
Develop protocols Guide students Interpret data Interact with physicians Report data Technology research Analyze data Write papersAnalyze proteinAssist with experimentsAttend investigator meetingBiomarker ResearchCommunicate with investigatorCollaborate with project teamConduct research at universitiesExecute scientific projectsEvaluate protocolsInteract with pre-clinical scientistsLiaise with research teamManuscript preparation and reviewOral presentationOperate research equipmentOrganise meetingsPresent data at congressPublication of articlesSolve problemsUse western blotting techniqueVerify dataWrite papersWritten presentation
Ph.D. in Bioengineering from IQS School of Engineering-The Ramon Llull University (Barcelona) in collaboration with the Vall d'Hebron Institute of Oncology (VHIO) in 2015
Master in Bioengineering from IQS School of Engineering-The Ramon Llull University (Barcelona) in 2011
Bachelor in Biotechnology from The Autonomous University of Barcelona (UAB) in 2009
Training and Certification
Basic Operator Training Course: Proteomics applications with a MaXis Impact System. Bruker Daltonics, Bremen, Germany in 2013 Training
Skyline Software (MacCoss Lab) Training, Bruker Daltonics, Bremen, Germany in 2013 Training
Practical course in proteomics for the identification of proteins by MALDI-TOF and peptides by MALDI-TOF-TOF mass spectrometry. Biochemistry Laboratory, IQS School of Engineering, Ramon Llull University (IQS-URL), Barcelona, Spain in 2011 Training
Expert has 2 publications (Will be avalible with full profile)