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Holding a PhD in biochemistry, I studied the interaction of endothelial and tumor cells through circulating microRNAs. MicroRNAs are small non coding RNAs regulating gene expression at post-transcriptional levels. Recently, they have been detected outside of cells in microvesicles called exosomes. These particles allow the communication between cells due to the transfer of their content. However, no information was known regarding the role of endothelial exosomes and their circulating microRNAs on tumor development. To investigate this topic, I used functional assays of angiogenesis and tumor growth as well as several techniques of molecular biology in order to characterize endothelial exosomes and analyze their microRNA content. This led me to the identification of an antitumor microRNA able to reduce tumor cell proliferation and invasion whose expression is regulated upon neoadjuvant chemotherapy treatments in the context of breast cancer.

Personal profile: Deep background in angiogenesis, tumor development, microRNA analysis and exosomes characterization. Good mastery of classical methods of molecular biology, common use of RNA and qRT-PCR techniques, practice of cell culture routinely and experience in in vivo experiments with mice.

Transversal skills: writing projects, reports and publications in peer-reviewed journals, managing projects and scientific staff, presenting data in internal and international meetings as well as in multidisciplinary teams.


Past Experience

  • Researcher Ph.D Student (FRIA) Liège, Belgique
    September 2010 --- April 2015

    Study the role of endothelial circulating microRNAs on the regulation of tumor development in the context of breast cancer.

    Characterization and functional studies of microvesicules (exosomes)
    Identification of microRNAs and determination of their activity
    Functional analysis of angiogenesis and tumor development
    In vivo studies of angiogenesis and tumor growth
    Set up of protocols for the analysis of circulating microRNAs

    Generic skills :
    Management of scientific staff
    Project writing and management
    Initiation and maintenance of collaborations
    Individual and team working
    Oral communication


Self Assessment :
ProactivityAnalytical thinkingAttention to detailProblem solvingCollaborationIndependencePerspectiveCuriosityOrganizationSociabilityCoordination


Self Assessment :
CancerCell Culture R&DDNAFlow CytometryFluorescence MicroscopyIn VitroIn VivoPCRWestern BlottingWomens Health Biochemistry Cell biologymolecular biologyMolecular & Cellular BiologyGeneticsBiomarkersProject ManagementRT-PCR Scientific writingAnimal ModelsCell biology
LinkedIn Assessment :
Project ManagementProject writingScientific staff supervisionTeam workingOral communicationsFluorescence MicroscopyWestern BlottingqPCRCell CultureCell biologyTransient TransfectionRT-PCRPCRRNA isolation

Skills and Expertise

Self Assessment :
Research at universities Develop protocols Guide studentsGuide staff Interpret data Write papersAdjust processes and methods Analyze dataBiomarker ResearchCollaborate with medical teamConduct literature searchesConduct research at universitiesmanaging a small teamOral presentation


  • Doctor of Philosophy (PhD) in Science in Biochemistry and molecular biology from Université de Liège in 2015
  • FELASE category C in Management of animal experiments from Université de Liège in 2011
  • Master's degree in Biochemistry and Molecular Biology from Université de Liège in 2010


BrightOwl Assessment:
Self Assessment:
Full Proficiency
Elementary Proficiency

Work Preferences

  • Notice Period:
    1 week
  • Positions I am interested in:
    Clinical Research Associate (CRA) associate Clinical Project Manager Clinical Research Associate (CRA) Clinical Project Manager (CPM) Postdoctoral Researcher Project Manager Scientist Clinical Research Associate (CRA) Clinical Research Manager Clinical Trial Manager Research Assistant
  • Work From Home:
    Yes, 0 to 2 days per week
  • Work Regime:
    Permanent position
    BrightOwl employee
  • International:


    Expert has 6 publications (Will be avalible with full profile)

Area / Region

Liège, Belgique


Driving License
  • Yes