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Summary

After achieving my scientific studies in chemistry and bioorganic chemistry, I did my Ph.D. in the field of amino acids and peptides synthesis and I acquired good knowledges of organic chemistry and advanced skills especially in peptide’s and nucleoside’s chemistry. A first post-doc at the REGA Institute in Leuven, then a partnership with Gilead Inc. (and an invitation to work in the Gilead’s research center in Foster City, US) enabled me to optimize all the issues of a scientific research life: strategy, optimization, open-mindedness.

Since 2007, I have worked in the Center for Innovation and Stimulation for Drug Design Discovery (CISTIM) in different positions. I started in this start-up company as project leader involved in an anti-viral project (four patents and one publication). Then, the company grew quickly from 8 until 24 people on 4 years (13 FTE scientists in the medicinal chemistry lab), so I applied to the position of Lab manager in order to enhance, rationalize and optimize the lab organization in a global point of view (general policy, safety & prevention issues, accounting/purchasing, partnership with providers…). In another hand, I actively participated to several projects (oncology, ion channels) as chemist to keep contact with the scientific team (screening, hits validation, H2L, SAR) because of my flexibility and adaptability with a highly developed team-spirit.

 

I think it is now time for me to evolve and assume new challenges. Persevering but not stubborn, flexible to reach and improve new knowledge, critical and team player, I have good communication skills that allow me to deal with diverse people (academic as well as company environment) that need to be brought together in order to ensure the success of the projects. I believe I can make a significant and valuable contribution in your company and I am highly interested to join your team.

Experiences

Current Experience

  • Lab Manager, Medicinal Chemistry
    Since April 2011
    Management: lab organization, general policy, safety & prevention issues Accounting/Purchasing: chemicals, consumables, equipment Med Chem: Drug discovery, H2L, SAR

Past Experience

  • Project Leader Leuven, Belgique
    July 2007 --- April 2011

    Manage H2L project: project plan (synthetic procedures, timelines, back-up series), IP, Biological results (SAR, ADME-Tox, Solubility)

    Meetings (presentation and minutes)

    Screening project: identify hit, selection of series, Hit resynthesis for validation

  • Postdoctoral Researcher Leuven, Belgique
    August 2005 --- July 2007

    Synthesis of new phosphononucleosides (collaboration with Gilead Sciences Inc.)

    Team leader of the HCV-Medicinal Chemistry team (3 chemists).

  • Postdoctoral Researcher Leuven, Belgique
    November 2003 --- August 2005

    A great collaboration on several projects with Prof. Piet Herdewijn:

    Delivery of antisense oligonucleotides using cholesterol-modified sense dendrimers

    Development of a new peptidic prodrug for antiviral use

    Synthesis of modified nucleosides and nucleotides

Personality

Self Assessment :
FlexibilityAdaptabilityInterest in knowledgeKindnessOrganizationSelf-disciplineAnalytical thinking

Knowledge

Self Assessment :
Biochemistry R&D Scientific writingChemistryEnglishHPLCLaboratoryMicrosoft OfficePowerPoint
LinkedIn Assessment :
Medicinal ChemistryChemistryDrug DiscoveryOrganic ChemistryHPLCDrug DevelopmentOrganic SynthesisNMRDrug DesignPurificationChromatographyNMR spectroscopySynthetic Organic ChemistryScientific WritingHealth & Safety AdviceCPR CertifiedFirst Aid certified

Education

  • Ph.D. in Bioorganic chemistry from Université Montpellier 2 in 2003
  • Post Graduate Diploma (D.E.A.) in Biomolecular Chemistry from Université Montpellier 2 in 2000
  • Master's degree in Organic Chemistry from Université Montpellier 2 in 1999

Languages

BrightOwl Assessment:
Self Assessment:
French
Native
English
Full Proficiency

Work Preferences

  • Work From Home:
    Yes, 0 to 5 days per week
  • Work Regime:
    Permanent position :    100% FTE
  • International:
    Yes

Publications

    Expert has 15 publications (Will be avalible with full profile)

Area / Region

Anvers, Belgique

Others

Driving License
  • Yes