Head of EMEA Bioprocess Services Brussels, Belgium
Since January 2016
Leader of 2 departments having distinct goals and business models:
– Bioprocess development team (Contract Development Organization - 10 people - Brussels), designing, optimizing and scaling-up/industrializing processes (Upstream and Downstream) on behalf of customers in the field of vaccines, cell therapy, viral vector and oncolytic viruses production which are mostly in the early phase of clinical development (preclinical to phase III).
– Bioprocess Application Specialist team (11 people located in Asia, Europe and US), Supporting Pall’s customers to transfer and industrialize their current process within single-use bioreactor platform (R&D and GMP environment). We also coach and guide customers in their bioprocess optimization and GMP room designs.
Additional Key roles
– Design and challenge customer’s therapy industrialization long-term plans by combining technical and market insights while taking into account customers constraints.
– LifeScience Market trend monitoring to identify the right organizations for co-development partnerships with Pall.
– Leading collaboration with UCL (London) PhD focused on cost modeling of Mesenchymal and CAR-T cell manufacturing.
– Led a 2 year viral vaccine industrialization project requiring active collaboration of several teams from 3 companies located in Asia, US and Europe. Once the process was optimized and scaled-up by our team, it was successfully transferred to the customer manufacturing site in Asia (for clinical trial phase I).
– Our Application Specialist team supported >150 bioreactor platform installations with a success rate (technology adoption) >80%. Performances were such that several customers published their results (Finvector, UCL, Molmed…)
Head of Cell culture Services Brussels, Belgium
November 2014 --- December 2015
Senior Application Specialist - Cell Culture Lab Associate Minneapolis, MN, United States
October 2012 --- November 2014
- Given the increasing customer support demand from the US customers, ATMI decided to setup a new Cell Culture department in the US
- 2 year expatriate mission in the US – Part of a team of 2 experts from Brussels.
- Set up an operational BSL2 Cell Culture Laboratory in an ATMI manufacturing site (with no bioprocess background) in
- Created a contract development organization business model and supported sales within the US ATMI organization leading to 4 contract signatures and 400% sales increase in 18months.
- Designed, managed and executed process optimization projects for large scale Mesenchymal Stem Cell, oncolytic virus and viral vaccines productions.
- Provided project management guidance as well as technical and scientific recommendation to customers, leading to successful process transfer to ATMI bioreactors (led to conference presentations by Lonza and Cellular Dynamics International)
Additional Key roles
- Ensured visibility of collaboration project successes by presenting at conferences (BPI, ISBiotech, NETIB), publishing posters, articles and answering interviews
November 2010 --- October 2012
- Led or contributed to the design, development, management and sales of several single-use bioreactors (iCELLis®, Xpansion®, Padreactor®)
- Tested and successfully managed installations of alpha and beta prototypes at customer sites, leading to successful process transfers into ATMI technologies.
- Optimized and scaled-up processes (suspension and microcarrier based cultures), from 1 to 1000L scale, producing mAb, influenza vaccine and Mesenchymal stem cells.
February 2009 --- November 2010
September 2008 --- February 2009
July 2007 --- February 2008
Comparative study of traditional cell culture supports (10L glass vessel) VS disposable bioreactors (2-50L) in the context of a recombinant vaccine produced with baculovirus insect cell expression system.
Intern Toulouse, France
July 2006 --- August 2006
Recombinant protein production (E.Coli) to make an enzymatic biosensor for algal toxin detection. Full project, from clone screening to evaluation of enzymatic activity.
Innovative thinkingAnalytical thinkingAssertivenessCollaborationFlexibilityCuriosityEfficiencyProblem solvingProactivityTrust
stem cellVaccinescost modelindustrializationlab managementProject ManagementTeam coaching R&DContract negotiationGood Manufacturing Practice (GMP)Cell CultureDownstream processUpstream processBioporcess developmentViral vector
Master's degree in Biotechnology from ENSTBB Bordeaux INP in 2008
in from Preparatory school - Toulouse in 2005