Since April 2013
Formulation R&D activities in a conjugate vaccine department (Hib, Pneumo and Maningococcal conjugate vaccine) for Parenteral conjugate vaccine product development. Troubleshooting in Formulation related problems in combination vaccine such as Pentavalent vaccine Improving stability of Hib-TT conjugates in pentavalent vaccine formulations. Significantly improving the adsorption of individual antigens i.e. Diptheria, tetanus and HbsAg and minimising the dosage regimen for parenteral vaccines. Supporting Assistant and Deputy Manager in preclinical formulation development and proof of concept studies.
September 2011 --- April 2013
Leading formulation team involving in designing and development of platform technologies for thermo-stabilization of vaccine formulations using different strategies including particle designing, encapsulation in microspheres, and industrial drying for Oral delivery of Rotavirus Vaccine Significantly reducing the distribution cost and footprints of existing vaccine by implementing a new viable packaging technology Managing project independently to obtain successful results, supporting associate scientist in preclinical formulation development and proof of concept studies. Perform Stability Studies as per ICH and WHO Guidelines, Data generation for filing, & generation of product specifications. Troubleshooting in formulation related problems. Pre-formulation and Formulation Development studies for Final Vaccine Product Development using Quality by Design(QbD), Design of Experiments (DoEs), Factorial Design (FD) approach.
Science Foundation Ireland (SFI) Research Fellow
January 2009 --- January 2011
Design localized Injectable nanoparticles made of Extracellular matrix based biomaterials for Intervertebral Disc Regeneration. Developed and optimized Microspheres/nanoparticles for aerosolized drug delivery (Aerogen Pvt. Ltd.). As Formulation Development Scientist, worked on natural biomaterials based micro and nanoparticles for therapeutic (Protein/gene/siRNA) delivery. Worked closely with Mylan Int. Pvt. Ltd. In relation to their Formulation Optimization Process. Assisted and Supported Ph.D. students for their characterization and animal studies.
Assistant Manager (NDDS)
January 2008 --- January 2009
Pre-formulation study design and experiments for injectable (Sterile) formulations for anticancer drugs While working in Process and Product Development Lab acquired the training in formulation optimization, Scale-up Technology for Injectables and particles based Oral Products. ICH Stability Studies, Data generation for filing, & generation of product specifications. Troubleshooting in formulation related problems. Fabrication of different batches as a part of NDA & ANDA filings to US, European and other regulated markets
Postdoctoral Research Scientist
December 2006 --- June 2008
Working in a Vaccine Development Research Team as Formulation Scientist for developing Nano/micro particulate based vaccine delivery for Hepatitis C and Viral Diarrhea in larger animals like sheeps, cattles etc.
Ph D in Pharmaceutics and NDDS from Dr. H. S. Gour University Sagar INDIA in 2006
M. Pharm in Pharmaceutics from Department of Pharmaceutical Sciences Dr. HS Gour University in 2001
B. Pharm. in Pharmaceutical Sciences from Department of Pharmaceutical Sciences, Dr. HS Gour University Sagar in 1999
Training and Certification
Radiation Safety Course by University of Saskatchewan Certification