During my career, I have build up expertise in protein production and purification, more specifically enzymes, recombinant proteins and monoclonal antibodies. I have designed industrial processes optimizing the fermentation, purification and final buffer formulation for proteins and antibodies applied in in vitro diagnostics. Currently, as the Head of Biomanufacturing in a SME active in the in vitro diagnostic sector, I am also responsible for implementing and improving the quality assurance system.
Apart from protein production and fermentation, I am also experienced in protein engineering and biocatalysis. I have engineered enzymes during my PhD to alter the substrate specificity and the stability. I have also developed industrial biocatalytic processes in the starch industry starting at the lab scale and scaling the process to final industrial scale.
I am interested in jobs in the (bio)pharmaceutical, chemical and biotechnological sector especially in biomanufacturing and biocatalysis. I am looking for jobs either in production or process development.
Head of Biomanufacturing
Since March 2014
* Development and scale-up of production processes for recombinant proteins and monoclonal Antibodies
* Continuous improvement of processes and quality system
* Transfer of processes to CMO* Implementing and improving quality assurance system
February 2013 --- March 2014
* Development of new products and processes using starch as raw material
* Upscaling of biocatalytic processes from lab to industrial scale
Ph.D. in Applied Biological Sciences
January 2008 --- December 2012
During my PhD program I have worked on the expression, characterization and engineering of sucrose phosphorylase aiming increased stability and altered substrate specificity. Besides my PhD research, I have also experience in bench scale simultaneous saccharification and fermentation of poplar. As PhD in Applied Biological Sciences and bioengineer, I am talented in implementing new knowledge and problem solving. During my PhD, I have developed good communication and project management skills and I am experienced in supervising and coaching students and lab technicians. I am very experienced in molecular biology, protein expression and purification, protein engineering, enzyme kinetics, bioinformatics and analysis (TLC, HPLC, HPAEC, …).
October 2011 --- October 2011
1 week stay: Molecular modeling and visualisation of protein variants supervized by Prof. Gert Vriend
February 2009 --- April 2009
Development of new strategies for protein engineering
Creative thinkingProblem solvingAssertivenessSociabilityFlexibility
Ph.D. in Applied biological sciences from Ghent University in 2012
Summer school in Glycosciences from The Graduate School VLAG in 2008
Master's degree in Bioengineering from Ghent University in 2007
Exchange program Biorenewable resources in from Iowa State University in 2006