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Summary

i have a great passion for Statistics accompanied by a strong Biological background. after a master’s degree in industrial Biotechnologies (Pharmacogenomics), i completed a phd in life and biomolecular science (open University, uk). meanwhile, i started attending Statistical courses spanning from the Analysis of genetic association studies to bayesian Biostatistics. in 2015 i also completed a second-level professional master's programme in Biostatistics and Epidemiology methodology at the University of pavia (italy). since january 2012, i am managing the Laboratory of molecular Epidemiology at the “golgi cenci” foundation where i am responsible for the molecular aspects of two Research projects: a prospective population-based study (“invece.ab” study, nct01345110 clinicaltrial.gov) and a randomized controlled trial (allena-mente” study, nct01793493 clinicaltrial.gov). i also provide methodological support to clinicians, on the basis of scientific collaboration, for science)" >Protocol writing, perform Statistical analyses and generate graphics and written summaries to enhance interpretation and presentation of study results.

core competencies • five years’ experience in cross-sectional and longitudinal studies of aging and age-associated diseases. • seven years’ experience in design, and Analysis of candidate-Gene case-control association studies. • previous Research experience with cellular and animal disease models. • working ability in italian, English and French. • Software : r (v. 3), Stata (v. 13), SPSS (v. 20). • author of 36 articles in peer-reviewed journals.

Experiences

Current Experience

  • Postdoctoral Researcher


    Since January 2012

    permanent Postdoctoral Researcher at “golgi cenci” foundation, abbiategrasso (mi), italy, since january 2012 (www.golgicenci.it).

    • write project deliverables (protocols, reports, articles, Literature Reviews);
    • perform Statistical analyses and basic Data Management;
    • provide methodological support to clinicians and basic researchers for design, conduct and reporting of human observational and intervention studies.
    • responsible of molecular and genetic Epidemiology of two ongoing studies: o “invece.ab” study: a prospective population-based study on Health and aging in elderly individuals (nct01345110 clinicaltrial.gov). role: search for risk factors and Biomarkers for age-related diseases. o “allena-mente” study: a randomized controlled trial evaluating the efficacy of cognitive stimulation (cs), vs a “sham” intervention, in elderly participants at risk to develop dementia (nct01793493 clinicaltrial.gov). role: investigate the influence of genetic variants on cs outcome.
    • molecular biology laboratory manager. role: manage a Laboratory Technician and undergraduate students to perform single Nucleotide polymorphism Genotyping, Gene and Protein Expression studies from peripheral blood mononuclear cells and Enzyme-linked immunosorbent Assays.
    • collaborator of the golgi cenci “brain bank”: a collection of human brain tissues of donors with a variety of neurological and psychiatric disorders, but also of non-diseased donors. role: Biological database management.

    Permanent postdoctoral researcher at “Golgi Cenci” Foundation, Abbiategrasso (MI), Italy, since January 2012 (www.golgicenci.it).

    • Write project deliverables (protocols, reports, articles, literature reviews);
    • Perform statistical analyses and basic data management;
    • Provide methodological support to clinicians and basic researchers for design, conduct and reporting of human observational and intervention studies.
    • Responsible of molecular and genetic epidemiology of two ongoing studies: o “InveCe.Ab” Study: a prospective population-based study on health and aging in elderly individuals (NCT01345110 ClinicalTrial.gov). Role: search for risk factors and biomarkers for age-related diseases. o “Allena-Mente” Study: a randomized controlled trial evaluating the efficacy of cognitive stimulation (CS), vs a “sham” intervention, in elderly participants at risk to develop dementia (NCT01793493 ClinicalTrial.gov). Role: investigate the influence of genetic variants on CS outcome.
    • Molecular Biology Laboratory Manager. Role: manage a laboratory technician and undergraduate students to perform single nucleotide polymorphism genotyping, gene and protein expression studies from peripheral blood mononuclear cells and Enzyme-Linked ImmunoSorbent Assays.
    • Collaborator of the Golgi Cenci “Brain Bank”: a collection of human brain tissues of donors with a variety of neurological and psychiatric disorders, but also of non-diseased donors. Role: biological database management.

Past Experience

  • PhD student (Open University, UK)

    October 2007 --- February 2012
    main findings: • identification of a novel genetic susceptibility locus for alzheimer’s disease using a Gene panel case-control approach. • first report of the neuroprotective role of sirt1 Protein against α-synuclein toxicity in cellular models of parkinson’s disease. • further evidence that environmental enrichment (ee) is a non-pharmacologic Strategy able to counteract cognitive deficits and neuropathological hallmarks in a transgenic mouse model of alzheimer`s disease. first report of sirtuins` involvement in the ee paradigm.

  • PhD student

    February 2009 --- March 2009
    - Training in real-time qrt-PCR, Western Blotting and Immunohistochemistry on human brain tissues

  • Fellowship

    January 2007 --- September 2007
    basic Research on aging

Personality

Self Assessment :
AdaptabilityAnalytical thinkingAttention to detailCollaborationCreative thinkingOrganizationProactivityStrategic thinking

Knowledge

Self Assessment :
Biostatistics R&DBiomarkersBiomedical SciencesCardiovascular diseasesClinical Data ManagementClinical Study DesignClinical study reportsClinical trial designClinical trial managementData AnalysisData cleaningDesign of Experiments (DOE) EpidemiologyMedical writingPharmacogenomics (study of genetic variation)Healthcare Information Technology
LinkedIn Assessment :
molecular biologyGeneticsMammalian Cell CultureBacterial Cell Culturemouse modelshigh-throughputLiquid Handling AutomationRandomized Controlled TrialPopulation-based studyPCRBiologia molecolareImmunoistochimicaCelluleELISAGenModelli animaliBiologia cellulareColtura cellulareTrasfezioneScienze naturaliResearchLife Sciences

Skills and Expertise

Self Assessment :
Analytical skills Analyze data Develop clinical trial protocolsWrite papersStatistical analysisR&Dproject managementPlanning clinical studiesPlan experimentsParticipate in medical reviewLead studiesInterpret dataInteract with pre-clinical scientistsEvaluate protocolsEnsure data consistencyDesign clinical trialAlzheimer Write papers Report data

Education

  • Second level Master Degree in “Biostatistics and Epidemiology Methodology” in from Università degli Studi di Pavia in 2015
  • Doctor of Philosophy (PhD) in Life and Biomolecular Sciences from The Open University in 2012
  • M.Sc Industrial Biotechnologies (Pharmacogenomics) in from University of Milano-Bicocca in 2006
  • B.Sc Molecular Biotechnologies in from Università degli Studi di Milano-Bicocca in 2004

Training and Certification

  • Introduction to Bayesian Methods in Clinical Research in 2015 Training
  • Statistical inference in biology and human science in 2013 Certification
  • Design and Analysis of Genetic-based Association Studies in 2010 Certification

Languages

BrightOwl Assessment:
Self Assessment:
Italian
Native
English
Professional Proficiency
French
Elementary Proficiency

Work Preferences

  • Notice Period:
    7 weeks
  • Positions I am interested in:
    BioStatistician Biomedical Scientist Clinical Data Manager (DM)
  • Locations I am interested in:
    France Germany Italy Switzerland
  • Work From Home:
    No
  • Work Regime:
    Permanent position
  • International:
    Yes

Publications

    Expert has 4 publications (Will be avalible with full profile)

Area / Region

Milan, Italy

Others

Driving License
  • Yes

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