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Experiences

Current Experience

  • Clinical Research Associate (CRA)
    Since June 2014

    In my function as CRA I have been assinged to several phase II and Phase III studies. Indications include; cardiology (devices), gastro-enterology, immunology (lupus) and oncology.

Past Experience

  • In-house Clinical Research Associate
    January 2014 --- January 2014

  • PhD Fellow
    January 2008 --- December 2013

    This thesis aims to:

    • Elucidate the phenotype and function of ex vivo circulating dendritic cells (DC) in multiple sclerosis (MS)
    • Compare the characteristics of in vitro generated monocyte-derived DC of MS patients with those of healthy controls.
    • Investigate the therapeutic potential of tolerogenic DC from MS patients for tailored immunomodulation in the treatment of MS.

     

    In this project following I aquired profound experience with following techniques:

    (i) Phenotypical and functionel assays:

    • Flow cytometry
    • ELISA
    • CBA
    • ELISpot
    • Migration assays

    (ii) Molecular biology:

    • Celtransfection with silencing RNA
    • Cell electroporation
    • mRNA isolation
    • RT-PCR
    • Western blot

  • Student
    September 2006 --- May 2007

    Master thesis: Involvement of CD11b+ and Th17 cell populations in the development of chronically relapsing experimental autoimmune encephalomyelitis (EAE) in mice and the role of interferon (IFN)-gamma.

     

    For this thesis I acquired experience with following techniques:

    • ELISA
    • Flow cytometry (intracellular and extracellular staining)
    • Cell isolation from bone marrow, lymph nodes and the central nervous system
    • Intraperitoneal and subcutaneous injections in mice

    Furthermore this project allowed me to:

    • Learn efficient and clear ways to communicate and report lab results
    • Improve my academic writing skills

Personality

Self Assessment :
CollaborationAttention to detailSelf-disciplineCoordinationIndependenceDependabilityOptimismCritical thinkingSociabilityCuriosity

Knowledge

Self Assessment :
Clinical research Animal models Cell biology Medical devicesAllergy and immunologyClinical monitoringClinical trialsCTMSELISAFlow CytometryGCPICH-GCPIn VitroIn VivoImmunologyMicrosoft ExcelMicrosoft OfficePCRPhase IIPhase IIIPre-clinical researchQuantitative PCR (qPCR)Scientific WritingSerious Adverse Event (SAE)
LinkedIn Assessment :
Cell CultureELISAFlow Cytometrymolecular biologyResearchMicroscopyCell biologyImmunologyMicrosoft OfficeCellCell Based AssaysEnglishClinical researchLifesciencesPCRScientific WritingdutchLife SciencesStatisticsAnalysisSPSSGraphPad PrismIn VitroCROICH-GCPClinical trials

Skills and Expertise

Self Assessment :
Guide students Interact with nurses Interact with physicians Monitor a clinical study Report data Search literature on clinical trials Write papersAnalyze dataAssess site feasibilityConduct close-out visitsConduct site initiationConduct monitor visitsConduct research at universitiesConduct literature searchesConfirm protocol complianceEnsure good clinical practice (GCP)Interact with pre-clinical scientistsManage Clinical Trial Management System (CTMS) Oral presentationReview exclusion criteriaReview inclusion criteriaSerious Adverse Event (SAE) ReconciliationSite managementObtain grants

Education

  • Ph.D. in Medische Wetenschappen from Universiteit Antwerpen in 2015
  • Master in Biomedical Science from Katholieke Universiteit Leuven in 2007

Training and Certification

  • Certificate of animal models in 2007 Certification

Languages

BrightOwl Assessment:
Self Assessment:
Dutch
Native
English
Full Proficiency
French
Professional Proficiency

Publications

    Expert has 5 publications (Will be avalible with full profile)

Area / Region

Mechelen, Belgium

Others

Driving License
  • Yes