Clinical Research Associate (CRA)
Since June 2014
In my function as CRA I have been assinged to several phase II and Phase III studies. Indications include; cardiology (devices), gastro-enterology, immunology (lupus) and oncology.
In-house Clinical Research AssociateJanuary 2014 --- January 2014
PhD FellowJanuary 2008 --- December 2013
this thesis aims to:
- elucidate the Phenotype and function of ex vivo circulating dendritic cells (dc) in multiple sclerosis (ms)
- compare the characteristics of In Vitro generated monocyte-derived dc of ms patients with those of healthy controls.
- investigate the therapeutic potential of tolerogenic dc from ms patients for tailored immunomodulation in the Treatment of ms.
in this project following i aquired profound experience with following techniques:
(i) phenotypical and functionel Assays:
(ii) molecular biology:
StudentSeptember 2006 --- May 2007
master thesis: involvement of cd11b+ and th17 Cell populations in the development of chronically relapsing experimental autoimmune encephalomyelitis (eae) in mice and the role of interferon (ifn)-gamma.
for this thesis i acquired experience with following techniques:
- Flow Cytometry (intracellular and extracellular staining)
- Cell isolation from bone marrow, lymph nodes and the Central nervous system
- intraperitoneal and subcutaneous injections in mice
furthermore this project allowed me to:
CollaborationAttention to detailSelf-disciplineCoordinationIndependenceDependabilityOptimismCritical thinkingSociabilityCuriosity
Clinical research Animal models Cell biology Medical devicesAllergy and immunologyClinical monitoringClinical trialsCTMSELISAFlow CytometryGCPICH-GCPIn VitroIn VivoImmunologyMicrosoft ExcelMicrosoft OfficePCRPhase IIPhase IIIPre-clinical researchQuantitative PCR (qPCR)Scientific WritingSerious Adverse Event (SAE)
Skills and Expertise
Guide students Interact with nurses Interact with physicians Monitor a clinical study Report data Search literature on clinical trials Write papersAnalyze dataAssess site feasibilityConduct close-out visitsConduct site initiationConduct monitor visitsConduct research at universitiesConduct literature searchesConfirm protocol complianceEnsure good clinical practice (GCP)Interact with pre-clinical scientistsManage Clinical Trial Management System (CTMS) Oral presentationReview exclusion criteriaReview inclusion criteriaSerious Adverse Event (SAE) ReconciliationSite managementObtain grants
Ph.D. in Medische Wetenschappen from Universiteit Antwerpen in 2015
Master in Biomedical Science from Katholieke Universiteit Leuven in 2007
Training and Certification
Certificate of animal models in 2007 Certification
Expert has 5 publications (Will be avalible with full profile)