BrightOwl Loader Loading

CMC - expert interested in jobs in the (bio)pharmaceutical, chemical and biotechnological sector?  I am looking for mangement - team leader jobs either in production or process development.      

 

 

Currently, I am a scientist team leader at Ablynx responsible for managing a small team of scientist developing analytical methods, the formulation and the characterization of protein therapeutics (DS & DP). In my role, I also cooridinate for certain projects the CMC pharmaceutical development and represent CMC in cross functional teams. In addition, I  organize and supervise project activities with external partners, chair project meetings and organize and supervise wet lab work.

I have an active management style, using my charisma, confidence and project authority in a way that draws my team together behind our common goal. I motivate them by inspiring them and showing them that their contributions make a real difference.  

In previous jobs,  I have build up expertise in protein production and purification, more specifically enzymes, recombinant proteins and monoclonal antibodies. I have designed industrial processes optimizing the fermentation, purification and final buffer formulation for proteins and antibodies applied in in vitro diagnostics. As the Head of Biomanufacturing in a SME active in the in vitro diagnostic sector, I was also responsible for implementing  and improving the quality assurance system.

Apart from protein production and fermentation, I am also experienced in protein engineering and biocatalysis. I have engineered enzymes during my PhD to alter the substrate specificity and the stability. I have also developed industrial biocatalytic processes in the starch industry starting at the lab scale and scaling the process to final industrial scale.

 

Experiences

Current Experience

  • Scientist - teamleader CMC

    gent
    Since February 2016
    people management
    • People management
      • Manage a team of scientists and lab technicians
      • Support and inspire team members
    • Analysis, characterization and formulation of protein therapeutics
      • Analytical method development
      • Formulation of DS and DP (different routes of administration)
      • Characterization of product related variants and process related impurities
      • Support CMC process development (USP and DSP)
    • Early and late stage pharmaceutical developmen
      • Represent CMC in interdisciplinary project teams
      • Summarize and report results
      • Contribute to regulatory dossiers (CMC-sections)
      • Support all departments with an overall product and process understanding
    • Project management
      • Organize and supervise project with external partners
      • Organize and chair project meetings
      • Organize and supervise wet lab work

     

     

  • Head of Biomanufacturing


    Since March 2014
    Monoclonal Antibodies

    * Development and scale-up of production processes for recombinant proteins and monoclonal Antibodies

    * Continuous improvement of processes and quality system

    * Transfer of processes to CMO

    * Implementing and improving quality assurance system

Past Experience

Personality

Self Assessment :
Creative thinkingProblem solvingAssertivenessSociabilityFlexibilityInnovative thinkingOrganizationResponsibilityStrategic thinkingResult OrientedSelf-confidenceStriving

Knowledge

Self Assessment :
people managementChemistry, Manufacturing, and Controls (CMC)FormulationAnalytical Chemistry
LinkedIn Assessment :
Biochemistrymolecular biologyEnzymesBiocatalysisAnalysisProtein EngineeringProtein ExpressionScientific WritingBioinformaticsProject ManagementEnzyme KineticsPurification

Skills and Expertise

Self Assessment :
Build the CMC development plan Interpret data Report data Technology researchChemistry Manufacturing and Controls (CMC) activitiesCoach staffCoordinate CMC-activitiesPeople managementproject management

Education

  • Ph.D. in Applied biological sciences from Ghent University in 2012
  • Summer school in Glycosciences from The Graduate School VLAG in 2008
  • Master's degree in Bioengineering from Ghent University in 2007
  • Exchange program Biorenewable resources in from Iowa State University in 2006

Languages

BrightOwl Assessment:
Self Assessment:
English
Professional Proficiency
French
Elementary Proficiency
Dutch
Native

Area / Region

Gent, België

Others

Driving License
  • Yes

Similar Candidates

Other Candidates in Belgium

Other Candidates in Ghent

Other similar Candidates in Ghent

Other Candidates

Most Recent Searches

Most Famous Searches

You might also like