Cancer is one of the leading causes of death across the globe. In fact, there were more than 18.1 million new cases of cancer patients in the last year around the world. To offer you more insights regarding the prevalence of cancer, the International Agency for Research on Cancer (IARC) has estimated that one-fifth of women develop cancer over their lifetime.
The rise in geriatric population combined with exposure to risk factors associated with economic and social development has propelled the need to invent an effective cancer therapeutics. The most frequently-observed types of cancer are lung, colorectal, and breast. The increasing concerns regarding the growing number of cancer patients suffering from cancer have further supplemented the need for a definite cure for cancer. Thus, major biotechnology companies such as F. Hoffmann-La Roche AG, AbbVie, Inc., Celgene Corporation, and Novartis AG are investing a huge pile of money to develop new treatments, therapies, and drugs to eradicate cancer.
According to a research firm, Allied Research Market, the global cancer therapeutics market is projected to reach $178.86 billion by 2023 with a compound annual growth rate (CAGR) during the period 2017–2023.
Israeli scientists claim to find a cancer cure
A small team of Israeli scientists recently announced that they have found the ultimate cure for cancer and will bring the drug in the market within a year. Moreover, they have claimed that the cure will be affordable, brief, effective, and will have minimum side-effects. Dan Aridor, the chairman of the board of Accelerated Evolution Biotechnologies Ltd. (AEBi), confirmed that they will provide the cure for cancer in a year’s time. AEBi has developed a SoAP platform that uses a combinatorial biology screening platform technology to offer functional leads such as an inhibitor, which are extremely difficult to target. However, scientists have not shared much about their discovery yet. However, they do offer the much-awaited hope for the cancer cure.
Launch of companies to deal with cancer relapse
HiberCell, a New York-based biotechnology company has been focusing on preventing cancer relapse and metastasis. It is observed that most of the cancer patients that surrender to cancer due to metastatic. Moreover, cancer recurrence is mainly driven by dormant disseminated tumor cells (DTCs) that remain undetected for a prolonged period of time. The company aims to detect weakest DTCs to prevent metastasis.
Alan Rigby, the Co-Founder of HiberCell, stated, “We always knew that DTCs are the major drivers of the cancer metastasis and this work is focused on defining the characteristic genetics and transcriptomics of latent disseminated tumor cells to improve patient outcomes and survival.” He believes that this approach would offer a lucrative opportunity to change the way of treating cancer.
While every cancer therapeutics in the world focused on how to cure cancer, very few think about the cancer relapse and how to prevent that. However, HiberCell builds a foundation to focus on novel tools to detect and explain survival mechanisms with therapeutics.
Genetically modified chicken eggs contain cancer-killing proteins
Scientists at the University of Edinburgh’s Roslin Institute took a novel step to help find a cure for cancer. They have produced genetically modified hens whose eggs are found to carry proteins that can help the human immune system to cure cancer. They found that the proteins–that are used to manufacture certain drugs including cancer therapeutics–can now be obtained from genetically-modified hen’s eggs. It is regarded as one of the most important discoveries in the cancer therapeutics as this could be a cheaper way to mass-produce cancer drugs. However, the drugs will undergo several tests before hitting the market.
The cancer drugs such as Avastin and Herceptin are protein based and can be produced with the use of cell culture technique. In this technique, the cells are removed from the animal and grown in a controlled artificial environment. However, such procedures are time-consuming, expensive, and can be produced in a small amount. Moreover, such methods involve complicated systems and require supplementary processing. On the other hand, this novel approach is more efficient and gives better yields while reducing cost-effective.
In this procedure, the genetically-modified hens lay eggs. From these eggs, the desired proteins are obtained using a simple purification method. It is observed that about three eggs are required to produce a sufficient dose of the drug. A chicken can lay up to 300 eggs per year, which are sufficient to mass produce the drug.
Such novel ways to produce therapeutics that can cure are the next big thing in the market. Moreover, major market players are now focused on producing a definite cure for cancer. There are few research institutes that claim that they are close to finding a permanent cure. However, such drugs are far away from making an entry in the market.
Last modified: February 13, 2019