As childhood cancer numbers rise, so does the call for concerted global action. Cancer cases in children have risen from 165,000 to 215,000 new cases for children 14 years of age and under, and 85,000 for children above the age of 14, according to a 2015 study conducted by the International Agency for Research on Cancer (IARC). On a global scale, childhood and adolescent cancer has nearly surpassed infectious diseases as one of the leading causes of childhood mortality (related to disease). There is a large disparity of children that suffer from cancer based on the wealth of the country they are from. For instance, 80% of registered children that live with cancer are from low and middle-income countries such as Africa, Asia, and Latin America, areas that do not have the specialized care and essential medications needed to treat such ailments.
February 15th is the day for everyone to come together to shine a light on this horrific disease. Today is the day that the Childhood Cancer International (CCI) containing 188 member organizations in 96 countries, and 1000 healthcare professionals from 110 countries who are members of the International Society of Pediatric Oncology (SIOP), ask everyone to come together and help solve this problem. I am not sure how to solve such a challenge directly at a molecular or cellular level, but I can aid in providing knowledge, informing people, and spreading the word.
So what are the top cancers plaguing our children and what do they do?
Leukemia accounts for approximately 30 percent of all cancers occurring in children. Leukemia occurs in the blood and bone marrow. There are 4 types of Leukemia, the most prevalent in children are:
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Children suffering from this disease will have symptoms of weakness, fatigue, bone and joint pain, pale skin, bleeding and bruising, weight loss, fever, and the list can go on. This is no way to be a kid, am I right? Leukemia is quite aggressive and the best course of action to date is chemotherapy as soon as possible. If you have a higher-risk leukemia the treatment will combine chemotherapy with a stem cell transplant.
Whats the purpose of this?
With high risk Leukemia’s it is pertinent to be incredibly aggressive. Chemotherapy uses harsh chemical substances to irradiate the cancer, but unfortunately the drugs are not as targeted as we might like them to be so they kill healthy and unhealthy cells. Because children are so small, they are are at a higher risk to develop the side effects of harsh chemotherapies such as catching life threatening infections, bleeding, low blood cell counts or related problems. Chemotherapy literally destroys the bone marrow, the stem cell transplant introduces blood forming stem cells into the body so they can differentiate into the various blood cells that are destroyed during high-dose chemotherapy, allowing the patient to withstand the treatment and giving them a better shot at a future. YAY SCIENCE!
#2 Brain and Spinal Cord Tumors
This is the second highest occurring form of cancer in children coming in at 26 percent. Because there is a wide spectrum of brain tumor types, the treatment can vary. Most cancers of this variety that occur in children begin in the cerebellum or brain stem (lower parts of the brain). This can stimulate headaches, vomiting, nausea, double or blurred vision, dizziness, trouble walking and using other motor functions, as well as seizures. Spinal cord tumors are less common, but do occur.
If you suffer from this cancer, you will have a team of doctors that will strategize the best way to approach your cancer. Treatment may include surgery, radiation therapy, chemotherapy, targeted therapy or the use of other drugs as treatments.
What do these treatments entail?
Surgery: Removal of as much of the tumor as possible.
Radiation Therapy: Uses small particles of high-energy x-rays to kill cancer cells.
Chemotherapy: Uses anti-cancer drugs introduced via IV or taken by mouth.
Targeted Therapy: These drugs target the properties in cancer cells that cause the cancer cells or aid in their proliferation. Note: This treatment is used minimally.
Alternative drugs: These drugs may not help in the cancers demise, but they may assuage the symptoms that they cause. These include: corticosteroids (reduce swelling, relieve nausea, vomiting, and headaches), anti-seizure drugs, hormones (helps n cases that the pituitary gland is affected by the cancer).
This cancer begins in the nerve tissue and accounts for 6 percent of childhood cancers. It starts in the nerve cells in a developing embryo or fetus and is rarely found in children over the age of 10. This cancer has no preference on residence, but most often than not starts in the abdomen where it is commonly noticed as swelling.
If a child comes down with a neuroblastoma, they can expect a team of modern day superhero’s to rush to their treatment. Treatment can include, surgery, radiation therapy, chemotherapy, a combination of high-dose chemotherapy/radiation therapy and stem cell transplant, retinoid therapy, and immunotherapy.
What are these treatments?
Surgery, radiation therapy, chemotherapy, and high-dose chemotherapy have been discussed thus far, refer to the treatments for #1 and #2 for a refresher.
Retinoid Therapy: This is recommended after high-dose chemotherapy and stem-cell transplant. Retinoids are related to vitamin A and are referred to as differentiating agents. It is thought that retinoids help cancer cells differentiate into normal cells.
Immunotherapy: Is a group of drugs designed to coax your own immune system into recognizing and attacking the cancer. One type, referred to as monoclonal antibodies, are paired with “immune system hormones,” called cytokines and together they help a child’s immune system to recognize and destroy neuroblastoma cells.
Pretty cool right?
The treatment for these cancers are involved, they require a team of diverse specialists, with state of the art equipment, medication, and facilities, something second and third world nations are not quite capable of providing just yet. There is a dire need for help and the first step is educating people about the issue. February 15th is the International Childhood Cancer Day, do your part to help irradiate this affliction, spread the word, knowledge is power!
#togetherforkidscancer #togethercreatingbetterfutures #ICCD #internationalChildhoodCancerDay #childhoodcancer #WHO
This article was written by Michelle Scire. Michelle Scire works as an analytical Chemist and Free-lance writer. You can visit her website at AlloKSci.com or catch her on social media:
Linkedin: Michelle Denise Scire
Individual bias is developed based on social environment, culture, upbringing and moral values. At times, we get negative vibes from a person for no justified reason. Unconsciously these feelings impact our judgments. The point is, without even realizing, such feelings result in wrong decisions. The responsibility of taking the right decision changes in professional life, especially when you are a part of the hiring team. Because the consequences of the wrong decision affect the entire organization in terms of money, time and productivity.
The identity discrimination should be removed from all the resumes prior to review by the hiring managers. Talent is beyond gender, location, nationality, age, and religion. The assessment of the resumes is supposed to be regardless of these identity priorities. In order to implement a transparent and fair recruitment system, these biased factors have to be eliminated.
Today isn’t only about the people we love. Today we treasure the people that help others every day by donating their blood. Thank you blood donors for taking care of our world!
You don’t have to suffer from Heart attack to keep a track of your “Heart Health Profile”. We owe this to ourselves to be self-aware of heart attack risks. You are never too young to start a Heart-Healthy Lifestyle. Every individual is at risk but the probability increases with some obvious factors.
Obvious Risk Factors
- High blood pressure or Cholesterol level,
- Unhealthy Diet
- Lack of Exercise/ Physical Activity
The question might seem a bit strange and I can already hear you say: “me of course!”
But not so in Recruiterland…
An entire multi-billion dollar industry has been built on the trade in résumés. Companies who work with third-party recruitment agencies to attract new employees, pay these agencies the so-called “finder’s fee” for each successful hire. Fees range from 15 up to 30% of a yearly salary (and in some cases even more). In case of a successful hire, the agency that first introduced the candidate to the company will be entitled to the commission. This is how the battle over résumés began and the reason why there are so many recruitment agencies today; it’s big business.
There is a lot of money to be earned with résumés and it’s a very competitive market so if you have been wondering why certain agencies are kind of aggressive in their approach and are trying to pressure you to accept job offers, this is the reason why. Don’t be fooled and make sure you stay in control of your own résumé and be picky about who you trust.
One might question the added value of intermediate agencies anyhow. Examples like Amazon, Uber, Airbnb and many others have shown that there are different ways. And to be honest, imagine what the effects on an organization could be if instead of having to spend all this money on fees for recruitment agencies, companies could spend it on training and development plans for employees. Wouldn’t that be a better investment?
But who can you trust? You can ask yourself a couple of questions:
- Are they transparent?
- Do they give you the company name and a precise job description? If they don’t, it’s because they are afraid that you apply directly to the company and in that case, they would miss out on the commission in case the company would hire you.
- Do they show interest in you when you describe to them what it is that you are looking for or are they just trying to sell you a job in for example sales because that is what you have always done before?
If they don’t listen to what you have to say, they only care about getting you into another sales function because that is where there will be the highest chance of a match, meaning, yes, commission.
- What’s in it for you?
If you decide to send them your résumé, what will they do for you? What is the service that you will receive from them?
- Are they making salary suggestions to you that sound a bit over the top to you?
Again, think about the 15-30% of the yearly salary that they will get when they succeed in getting you to sign a contract.
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- If you look for a job on our platform you will always see the precise job description and company name. When you open a full job description, you get redirected to the company’s website.
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